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Abstract: The spice Acalypha indica belonging to Euphorbiaceae family has different remedial properties, in this paper we assessed the phytochemical, antiinfective and against oxidant activities of Acalypha indica leaves in various dissolvable extractions like ethyl acetic acid, hexane methanol and petroleum ether. New leaves of the sample plant were picked and hide dried. Dried leaves were handled to get powder, then processed to Soxhlet extraction using solvents and concentrates were logically procured. Phytochemical assessment was coordinated considering recent methods. Due eventual outcomes of phytochemical examination, which resulted in identification of saponin, Phenols, alkaloids, Flavonoids and Amino acids. Leaf concentrate of methanol have shown the most raised adversary of oxidation limit than hexane, ethyl acetic acid derivation and oil ether. Antimicrobial activity was tested on microorganisms like Bacillus Sps, E. coli, Pseudomonas Sps and Streptococcus Sps. A generally raised worth of zone of block was detected in methanol solvent eliminate against E. coli. These results confirmed that Acalypha indica leaf extracts has fundamental phytochemicals, antimicrobial and disease counteraction properties. Therefore, the phytochemical extracts from this plant can be examined further for drug assessment for finding therapeutic biomolecules for antimicrobial and antioxidant activities.